De-nol, instructions for use

1

Pharmacological effect of the drug

De-Nol has several pharmacological properties. All of them are associated with the fact that the main active substance in de-Nol is the bismuth of tricalous dicitrate.

• Binding and healing. Vismuth Trikalia Diciterate is capable of besieging proteins, which, interacting with gastric juice, form the so -called chelat compound. The latter forms a protective film on an ulcer or erosion damage to the stomach.
• Bactericidal. Vismuth Trikalia Dicitrate inhibits the activity of Helicobacter pylori bacteria. At first, harmful bacteria reduce their mobility, then lose the ability to introduce themselves into cells and at the end - die.
• Gastrocytoprotective. Penetrating into the deepest layers of tissues, the bismuth of tricalya dicitrate destroys bacteria that managed to multiply under the gastric mucosa. This deep effect eliminates the risk of a repeated occurrence of an ulcer or erosion.

2

Who shows De-Nol

The drug is prescribed for the following diseases:

• Stomach ulcers or duodenum.
• Gastritis and gastroduodenites.
• Ulcerative or erosive lesions of the stomach and duodenum, which may occur due to uncontrolled intra-steroidal drugs from various inflammations.
• Irritable bowel syndrome due to prolonged diarrhea.

De-Nol is also used in complex therapy aimed at destroying Helicobacter Pylori. In this case, it is prescribed in combination with antifungal drugs (for example, metronidazole), proton pump inhibitors (for example, omeprosol) and antibiotics (for example, tetracycline or amoxicilin).

3

How to take de-Nol

The standard treatment regimen using De-Nol is this:

• Children after 12 years old and adults - 1 tablet 4 times a day before meals or 2 tablets 2 times a day (also 30 minutes before meals).
• Children from 8 to 12 years old - 1 tablet 2 times a day 30 minutes before meals.
• Children from 4 to 8 years old - 8 mg ha 1 kilogram of child weight per day. The total daily dose is divided by 2 times and given to the baby before meals.

The tablets are washed down with a small amount of drinking water. The course of treatment de-nolu is from 4 to 6 weeks. With neglected ulcers, the doctor can extend the treatment for up to 8 weeks. Helicobacter pylori treatment regimen (de-nolo + other drugs) in each case, the doctor may prescribe different ones. It depends on the degree of infection with bacteria, which is determined by the analysis of the blood, respiratory test or smear from the oral mucosa.

4

Contraindications to the receiving de-nol

De-Nol cannot be taken by pregnant and nursing women, as well as people who have kidney diseases. Children under 12 years of age should take the drug with particular caution and only under the supervision of a doctor.

5

Side effect of de-nol on the body

With the example of pills on the patient’s body, a rash and itching may appear. From the gastrointestinal tract, nausea, vomiting and frequent urge to the toilet (diarrhea) or stubborn constipation are possible. With an overdose of pills, feces can darken, and an increased concentration of bismuth is found in the urine and blood. When de-nol cancellation, all these phenomena disappear.

Bismuth, which is the active substance of this drug, in large doses can cause the development of encephalopathy. To prevent this from happening, it is impossible to take any other drugs containing the bismuth with de-Nol.